Frequently Asked Questions

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Side Effects

For more than 30 years, extensive consumer use and numerous clinical studies have shown that Advil®, when used as directed, is a safe and effective OTC pain reliever. The active ingredient in Advil® is ibuprofen, and the over-the-counter dose for Advil® is lower than prescription ibuprofen. See ‘Health Conditions’ section for additional information.
No. Ibuprofen is not habit forming, nor does it demonstrate addictive properties. Studies indicate that ibuprofen affects the body (peripherally active), not the brain (not centrally active). Advil® is nonnarcotic.
Effects of ibuprofen on the liver are rare but may include liver disorder, abnormal liver function, hepatitis and jaundice, and, they may occur at higher than recommended OTC doses. When taken according to the label, adverse effects of fast acting Advil® Film-Coated Tablets on the liver are uncommon. If you have liver cirrhosis or other concerns about taking fast acting Advil® Film-Coated Tablets, consult a physician.
No. Keep in mind, while no observed tolerance build up has been shown, over-the-counter pain relievers (including Advil®) should not be used for longer than 10 days unless directed by a physician.
While ibuprofen may cause ulcers, they’re usually the result of higher prescription doses or when administered for long periods of time. Studies have proven that Advil® is safe and effective when used as directed. If you have a history of stomach problems, such as heartburn, consult your doctor before using Advil®.
When taken as directed, adverse effects of Advil® on the kidneys are uncommon; however, higher doses can produce adverse effects on the kidneys. Consult your physician before taking Advil® if you are taking a diuretic, have kidney disease or have any other concerns.
When taken as directed, adverse effects on the liver are uncommon. Effects on the liver are rare but may include liver disorder, abnormal liver function, hepatitis and jaundice, and, they may occur at higher than recommended OTC doses. Consult your physician before taking Advil® if you have liver cirrhosis, or any other concerns about taking this product.

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