Frequently Asked Questions

Choose from the topics below to learn more about what’s important to you.


What’s the difference between Tylenol® and Advil®?

The pain reliever in Advil® is ibuprofen, which is part of a class of drugs called non-steroidal anti-inflammatory drugs (also known as NSAIDs). Advil® does not contain acetaminophen, the active ingredient in Tylenol®.

We’ve put Advil® up against Tylenol® in 30 different pain studies. Advil® remains the undefeated champion of tough pain relief.

Is Advil® opioid free?

Yes, Advil® is opioid free. Advil® (Ibuprofen) is a NSAID (Non Steroidal Anti Inflammatory Drug) which treats acute pain and fever by blocking the formation of pain promoting chemicals at the source and is not addictive. Opioids, on the other hand, work on receptors in the brain to block the transmission of pain. They’re addictive and cause side effects like sedation and euphoria.

What are the differences between prescription opioids and OTC pain relievers?

Like the name implies, over-the-counter pain relievers can be bought without a prescription and are used to treat moderate pain and fever. Opioids are a different class of drug that treat severe or chronic pain and require a prescription from a doctor. If you want to learn about how Advil® and opioids interact, click here.

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Call a customer service representative toll-free at:
1-800-882-3845 (1-800-88-ADVIL)
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Pfizer Inc., PO Box 1043
Kings Mountain, NC 28086

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