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FAQs: Comparison

  • The pain reliever in all Advil products is ibuprofen which targets pain at the source. Acetaminophen, the active ingredient in Tylenol, blocks off pain signals. Advil Dual Action is first and only FDA approved combination of the two. It is also the only Advil product that contains acetaminophen.

  • Yes, Advil is opioid free. Advil (Ibuprofen) is a NSAID (Non Steroidal Anti Inflammatory Drug) which treats acute pain and fever by blocking the formation of pain promoting chemicals at the source and is not addictive. Opioids, on the other hand, work on receptors in the brain to block the transmission of pain. They’re addictive and cause side effects like sedation and euphoria.

  • Like the name implies, over-the-counter pain relievers can be bought without a prescription and are used to treat moderate pain and fever. Opioids are a different class of drug that treat severe or chronic pain and require a prescription from a doctor. If you want to learn about how Advil and opioids interact, click here.