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Safety FAQs

  • What is Diphenhydramine Citrate?

    Diphenhydramine Citrate is a gentle, non-habit forming sleep aid that helps you get a full night’s sleep. It has been used for over 50 years, and has had a long history of safe and effective use when used as directed.

    Each Advil PM caplet contains 200 mg of ibuprofen and 38 mg of diphenhydramine citrate. This patented bi-layer formula not only reduces your pain, it shortens the time it takes to fall asleep and increases the duration of your sleep.

  • What is ibuprofen?

    Ibuprofen is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAID) that has been relieving pain for quite a while. In fact, the first clinical trials of ibuprofen began in February 1966 and over 30 years of clinical studies prove that ibuprofen, the pain reliever in Advil PM, is effective on pain. NSAIDs, nonsteroidal anti-inflammatory drugs, are a group of chemical compounds that often are chemically unrelated but share therapeutic actions such as analgesic (pain-relieving) and antipyretic (fever-reducing) effects. Ibuprofen is just one drug in the NSAID class.

  • Is Advil PM safe?

    For more than 30 years, extensive consumer use and numerous clinical studies have shown that, ibuprofen, the pain reliever in Advil PM, and diphenhydramine, the sleep aid in Advil PM, are both safe and effective when used as directed. Please refer to the full product labeling for additional safety information related to Advil PM.

  • Can I use Advil PM products beyond the expiration date?

    It is not recommended to use the product past its expiration date, as the effectiveness of the ingredients is only assured until the date printed on the package.

  • What’s the difference between Tylenol PM and Advil PM?

    The pain reliever in Advil PM is ibuprofen, which is part of a class of drugs called non-steroidal anti-inflammatory drugs (also known as NSAIDs). Advil PM does not contain acetaminophen, the active ingredient in Tylenol PM, and it’s been proven that Advil PM gives you a better night’s sleep than Tylenol PM because you’ll spend less time lying awake with annoying aches and pains and more time asleep.